Ed Rybicki πΏπ²πΏπ¦π·π
@edrybicki.bsky.social
Semi-retired biotechnologist and virologist, interested in making vaccines, lover of 70s rock and hard SF. And good red wine. Posts are both personal and professional, and may include music and/or strong opinions. And possibly zombies.
created September 7, 2023
3,596 followers 253 following 18,770 posts
view profile on Bluesky Posts
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Just done a tour of Xwitter, and reminded myself forcibly why I donβt use it regularly any more. Rampant crypto ads, unhinged idiots swamping posts by respected folkβ¦time to delete, I think.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
You know you could buy a smart new one, right? Right??
Angie Rasmussen (@angierasmussen.bsky.social) reposted
This is how outbreak response should go: fast, transparent, and actionable. Ebola will continue to spill over into humans. So will other viruses, some new, some old. Having this response capacity is what controls outbreaks, stops epidemics, & saves lives.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Pragtig!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
βmRNA vaccines have a superpower that no other type of vaccine can currently match: They can be quickly updated and manufactured within two to three monthsβ. Wrong: DNA vaccines can also do this, and plant-made protein vaccines too. Project Blue Angel: 10-40 mill doses flu vaccine in 1 month.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
My daughter has done well out of us: she is a natural antiquarian, and looks really good in my wifeβs old clothes. She politely declined my old Indian cheesecloth embroidered shirts, though.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
I did just rip 150 CDs that I didnβt feel like rebuying digitallyβ¦.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Noooooooo Larry! Not the vinyl!! Or box it and ship it hereβ¦.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
I have rugby shirts from schools I last attended in 1968 and 1973. And my Sgt Pepperβs 33 1/3 rpm mono vinyl from 1968.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Kudos indeed for sequencing and sharing from DR Congo!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Amazing!π€© But you might be surprised: streaming stuff is compressed pretty drastically in terms of tonal range and even volume variations. I have a turntable with amp and iPod connections AND a USB slot: very useful. Connected to my 1983 NAD3020 amp and big speakers. You know you want toβ¦ππΌπΈ
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Oh, yes!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Howzit, boet.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Youngster. I got there first!
Amy Maxmen, PhD (@amymaxmen.bsky.social) reposted
DRC just declared an Ebola outbreak with 13 deaths so far.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Influenza virus Rhinovirus π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
We bought, in the face of people saying "use Google maps for Namibia!", a big plasticised map from Tracks4Africa. It worked so well - cell phone reception across northern Nam was CRAP, generally - that we did the same for northern South Africa. Invaluable!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
REALLY cool example of extreme genetic parasitism: I can see this being incorporated into SF stories really soon...eh, @aptshadow.bsky.social? π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
π² TFW you discover in a talk at a retreat on something not remotely in your field of expertise that you may be at increased risk of resistant hypertension due to your statin regime...π©
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Oh, to have the physique and health again...with present levels of experience and/or wisdom! π©
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Nahβ¦!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
You were 21?!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
It would be nice if you did posts that actually tell a complete story without having to link out to a blogβ¦just saying.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Those grated carrot salads with sugarβ¦! Ghastly.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
You might be amazed at how many people just keep on rolling. Not if Iβm chairing, though B-)
Jenka (@jenka.bsky.social) reposted reply parent
Yes, I have written about this. I think the point of my original post was not understood correctly. medium.com/@socialcreat...
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Sounds like several speakers from the US that I have heard squash 3 20 minute talks into 1 30 minute one - that runs 10 minutes overtime. Except when Iβm chairing.
Judy Stone (@drjudystone.bsky.social) reposted
More evidence for role of #antihistamines in potentially preventing #Covid infections--this time w nasal spray. www-nbcnews-com.cdn.ampproject.org/c/s/www.nbcn...
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Fuck, I need to add a few things to my block list if I'm to keep my blood pressure down and awful sense of impending disaster at bay. Like Vought, NIH, CDC, Congress, Senate, US, USA...π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
That's what I love about this Universe: you just wait, and more good stuff emerges π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Hey, I took 30 years to NOT finish my definitive Introduction ot Molecular Virology - until @ajcann.bsky.social walked away from his book after 30-odd years, and I got to revise it for the 7th Edition. Suddenly finished!! Get a co-author π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Stupid bastards π‘
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
I was replying to @signfire.bsky.social - a lot of people don't appreciate that quite a few cancers are very strongly linked to viruses. You are not among them!π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Way longer than ten years, and causation is a fact in the case of cervical cancer and HPV - and strongly linked with hepatocellular carcinoma and HBV, and nasopharyngial carcinoma and Burkitt lymphoma and EBV.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Welcome - to the fun house...π
Raywat Deonandan (@deonandan.bsky.social) reposted
I love looking at this graph, showing it to my students, and sharing it on social media, even though it unerringly brings out the trolls. This is the efficacy curve of Pfizer's mRNA COVID vaccine. This, people, is what ended the emergency phase of the COVID pandemic. Despite what RFK Jr says.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
One aspires! π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Gary on Camping @profgdfoster.bsky.social
Jenka (@jenka.bsky.social) reposted
Before COVID we didnβt even know a virus causes multiple sclerosis. They just figured out how it does it. www.nature.com/articles/s41...
Kerstin GΓΆpfrich (@kgoepfrich.bsky.social) reposted
RNA droplets that grow and segregate by ribozyme catalysis. Check out our latest preprint www.biorxiv.org/content/10.1101/2025.08.29.673008v1
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
As a longtime (since mid-60s) fan of SF/F, I can attest that βitβ is in rude health, and not even thinking of dying. There is an amazing amount of stuff out right now, with a glorious diversity of style, theme,, and content - and it is wonderful. As it was in the 60s-70s with the New Wave!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Martha Wellsβ Murderbot series. Mainly novellas, 2 short novels. ALL first person; REALLY good!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Unimplementable because it was SO expensive to make synthetic mRNA, and very difficult to scale it up. Itβs much cheaper now, obviously.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Ismail, we have met: in the days of the old Mail & Guardian chat group. Once, for a coffee. And some discussion about Grand Funk Railroad B-) So over 25 years ago? If youβre in CT, we can rectify the gap, though?
Josh Crews (@joshcrewsreally.bsky.social) reposted
Will Santino. #comics #art #cartoon
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Thanks! Oh, it was pretty quick, as noro normally is, apparently. But my ribs and intercostal muscles ache, my back is spasmingβ¦where is that damn Icon Genetics plant-made vaccine?!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Get better soon!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Drop an old person you're going to turn into in the future. Or are now.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Yup! And violentβ¦upchacking, shall we say.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
All one can ask!
π¨π¦Ian - #RLessThanOne (@simpson-ian.bsky.social) reposted reply parent
Long distance transport through a building ventilation system.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
βIβm watching you, hoomanβ¦just donβt turn your back!β
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Norovirus!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Have 3 copies π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Done, with yoghurt. π
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Oh, itβs having a whale of a timeβ¦!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Need..toβ¦captionβ¦aβ¦kitty picture!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Youβre young, mate!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
So the obvious symptoms no longer present - but now a serious fucking headache. I donβt DO headaches; Iβm lucky - and serious lethargy. Viruses: canβt love them allβ¦!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Nah: thatβs been a 3rd world country recipe for longer than I know.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
First bout in YEARS!! Out of the blue, as it were.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Welkom in Nederland!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Addis Ababa: all of the above (except itβs new), AND no announcing gate changes.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
A WARM good morning! Happy Vaccination Day Bowie!!
The Spaceshipper π (@thespaceshipper.com) reposted
I invoke for September: - The first teaser for The Mandalorian and Grogu - The second trailer for Project Hail Mary - The first teaser and release date for For All Mankind Season 5 - A first look at Star City (spin-off of For All Mankind) - Something next Trek movie - First look at Blade Runner 2099
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
On our way, are we??
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Crossed messaging - thatβs my present-state GIF!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Teaspoon of salt, dessert spoon of sugar, in 1 litre. The go-to rehydration remdy.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
This one?
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
PS: thanks!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Understand - yes. But it does nothing for the symptoms. Only codeine does that.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Having got up close and personal with what has to be a norovirus infection that manifested last night, I can attest that there is a cloth-head syndrome that goes with energetically evacuating your stomach, that is seriously debilitating. That, and a monster headache. Fuck!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
I DO like that animation!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
That is a SERIOUSLY good run of two series - third, not so much. Animated shorts (with quality ranging from hard-to-tell-not-live to very stylised. Stories from Neal Asher, John Scalzi, Alastair Reynolds - brilliant!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Did you see the Love, Death & Robots episode?
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Zima Blue, anyone?
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
And then there was βmisledβ. Obviously the past tense of the verb βto misleβ, pronounced myzel. I though that until was 25 or soβ¦.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Well, obviously, one would take more than one� That would come with The Who.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
And??
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
On the contrary, alive and very well!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
I am sure I got a Candida infection up my nose from a lab strainβ¦βSniff this plate!β we were toldβ¦.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Me talking with The Daughter about Deep Things. Like red wine πππ·
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
And if you had any sense, you used those autoclaved serological pipettes plugged with cotton wool at the top end!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Know by mouth feel: like one of @aptshadow.bsky.socialβs engineered reptiles.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
You should not sit on the floor, period!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
So are quite a few of usβ¦personally, Iβve had acrylamide mix, phenol/chloroform and various solutions into my mouth. Autopipettes couldnβt have come too soon!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Ever had that experience when you think of doing some online food shopping, get the app, set up your account, do the 2-factor thing, navigate the menus, fill up the basket with βOoh, that looks nice!β things, and get to what you wanted - to see itβs not in stock. Screw it, I drove to the nearby Spar
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
I lie: some F, too.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Mouth pipetting bacterial suspensions: natureβs way of immunising scientists!!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
Your house is burning and you can only save one record:
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Yabba dabba!
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Yup! But a cool 13.
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
OK, my lunch date is delayed, so I end up listening to this, also from 1968. Now you can too. www.youtube.com/watch?v=UeIc...
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social) reply parent
Alastair Reynolds wrote a trilogy of really good future pirate novels suitable for teens a while back? www.google.com/search?q=ala...
Ed Rybicki πΏπ²πΏπ¦π·π (@edrybicki.bsky.social)
OK, more flowers - and rocks! With a little natural rock garden.