✍️ New article: "How Wolbachia bacteria could help us tackle some of the world’s most neglected tropical diseases"
Researching macrophages and neutrophils in TB || Entomology PhD, ticks and tick-borne bacteria || macro photography and reef aquaria enthusiast || opinions my own || Northern Minnnesotan
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✍️ New article: "How Wolbachia bacteria could help us tackle some of the world’s most neglected tropical diseases"
Our PostDoc Richard contributed to a review on coronaviruses: From zoonotic spillover to endemicity: the broad determinants of human coronavirus tropism Together with @pfaenderlab.bsky.social he dives into the mechanisms that determine host specificity of CoVs. journals.asm.org/doi/10.1128/...
Absolutely monstrous
Delighted to share our latest review article written by @gnna.bsky.social on #neutrophil #ageing #inflammageing #frailty #immunosky 🧪 @livuni-ilcams.bsky.social @vivensa.bsky.social academic.oup.com/jleukbio/adv...
Just a reminder before the “big announcement” today. Autism was discovered in 1911 and the modern definition of Autism came in 1943. Tylenol wasn’t widely used until the 1950s. Anyone trying to tell you that Tylenol causes Autism isn’t someone that should be taken seriously.
The word “autism” was first used to describe behavioral differences in children in 1911 but autism has been documented using available records going back to the 1700s (definitively) and further. Acetaminophen (Tylenol, paracetamol) was discovered in 1878 and first sold in the United States in 1950.
Are you with us in the battle against misinformation? If so, we’d appreciate your support. Just this week, we’ve explained the importance and safety of vaccines… 🧵 buff.ly/cRsOxNT 🩺 🧪 #VaccinesWork
This is Biggie. He can't believe this was your pick for movie night. Gonna need a cartoon before bed so he doesn't have nightmares. 14/10 (TT: x_gzm0714)
"The science is compelling, climate change is a clear and present danger for the health of our patients and communities. The National Academy of Science Engineering and Medicine report confirms what the medical community already knows: climate change is harming our patients..." (1/3)
Find the plasmids containing dMCP and dPCP here! www.addgene.org/browse/artic... Thank you @johntngo.bsky.social for sharing 🧬
Whoa! Super cool!
The @washingtonpost.com story on Tylenol & autism leaves out a MAJOR 2.5M sibling-controlled study of children in Denmark, which "found no evidence that acetaminophen use during pregnancy was associated with children’s risk of autism, ADHD or intellectual disability." jamanetwork.com/journals/jam...
Scientists have created the first ever viruses designed by AI, and they’re capable of hunting down and killing strains of E. coli go.nature.com/4nA8E6p
ICYMI: Cancer can activate the coagulation system, but how do anticoagulants affect checkpoint therapy? Wolfram Ruf & team show coagulation signaling subverts the tumor-DNA immune response & anticoagulants with ICB synergistically reduce tumor growth in mice: buff.ly/LqkEAX7
Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.
Important to remember that H1B visa holders have their whole life in the US. The home they rent or own is here. Their family. Their kids go to school here. Being locked out of the US is also in many cases rendering them homeless and away from their family, with no obvious path to return
Everything* *except phos? Is classic form/MeOH still best there? I’m an eager flow amateur. I had to do pSTAT5, but I’m allergic to proprietary buffers. Luckily I found this explicit protocol paper from 2003: form/MeOH worked great 1st time, every time since🥰 onlinelibrary.wiley.com/doi/full/10....
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
This is absolutely brilliant🤩. Finding the right buffer set that you can use across most all #FACS needs… And at a fraction of cost… Love it👇🏻 Kudos to @labliston.bsky.social to dedicate time and effort to this….
1/ Two days of ACIP chaos: Self-described "rookies" eliminated universal COVID vaccine recommendations, added FDA-debunked theories to consent forms, voted outside their legal authority. They literally don't know what they're doing or what they're allowed to do.
🚨🎉 The Center for Evolutionary Biology and Medicine (CEBaM) at Pitt is delighted to announce the winners of this year's Catalyst Award program. This year, Catalysts were designated for science communication projects that engage wider audiences in the field of evolutionary biology and medicine. 🧵🥁
Important to note that CDC recommends HepB vaccination at biirth REGARDLESS of mother's infection status because the protective window is only ~12 hours, test results can be delayed or in error, vaccine protects infants when maternal status is unknown, and starting vaccine early improves adherence.
I cannot stress this enough: do not use email for organizing. Set strict retention so emails delete after a short period of time. Assume every Big Tech company will rat you out to the gestapo without lifting a finger to protect your rights theintercept.com/2025/09/16/g...
Rifampicin is more effective against biofilm infections because it targets biofilm-forming mutants that are highly resistant to other antibiotics @niaidnews.bsky.social www.science.org/doi/10.1126/...
I just saw a patient with liver cancer from hepatitis B that was acquired at birth. Vaccination would’ve prevented it. There’s been a 99% reduction in annual childhood hep B infections since 1991 thanks to universal birth dose vaccination. We can’t afford to roll back that progress.
GOOD NEWS! A new cancer vaccine has shown progress in triggering POWERFUL and LASTING immune responses in patients with pancreatic AND colorectal cancer. The vaccine, known as ELI-002 2P, targets mutant KRAS proteins AND had a huge impact on PREVENTING or DELAYING cancer recurrence in patients.
Tuberculosis (TB) remains one of the world’s leading infectious killers, and NTM infections are rising. #JClinMicro invites submissions to our "Diagnostic Testing for Mycobacteria" series. 📄 Share your research now → asm.social/2B6
"And the best thing about the polio vaccine is that it even protects people who don't believe in it."
Delighted to review the latest findings on how malaria parasites get into our blood cells and how we might stop it!
#WeekendRead #InterferonPower! Hegde, @miriammerad.bsky.social &co show @nature.com that #tumor-derived factors drive NRF2 activation in bone marrow myeloid progenitors, dampening IFN-I/-III responses & favoring emergence of immunosuppressive monocyte-derived macrophages!
Some macrophage subsets can curb deleterious inflammation in mycobacteria-driven granuloma @pnas.org #IDSky #TBSky pubmed.ncbi.nlm.nih.gov/40729382/
#Tuberculosis severity varies widely between people; why is this? This study uses the #CollaborativeCross mouse panel to identify the protease #cathepsin Z (CTSZ) as a conserved regulator of #TB outcomes via its influence on CXCL1 in mice & in humans @plosbiology.org 🧪 plos.io/4phwRA8
A deep dive into the destruction of US cancer research by @jonathanmahler.bsky.social “It’s an absolutely unmitigated disaster,” a former top official at NIH told him. “It will take decades to recover from this, if we ever do.” Gift link: nyti.ms/48iH3Cr
Nature research paper: Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours go.nature.com/48fgQ7H
🎉🎉🎉Shout out to Kaiser Permanente - they recently updated their website to say that they WILL be covering COVID-19 vaccines all of their members 6 months old and up!! 🎉🎉🎉🎉 Thank you KP - let's hope their announcement kicks off more like it kp.org/covidvaccine
A couple of those authors went hard on defending their 'work' in the other place. I'm sure there are threads citing 'bias' and 'censorship by the scientific community' being written over there right now.
New preprint! 🥳🎉 We looked at viral coinfection patterns at the largest scale ever in wildlife. We found a strong association among CoVs, PMVs, and influenza A, and higher coinfection rates in wildlife trade; plus, evidence that bats accumulate persistent infections. www.biorxiv.org/content/10.1...
Open tenure track assistant- or associate-level faculty position in the University of Pittsburgh's Center for Vaccine Research. Great science, great facilities, great colleagues - come work with us! jobs.sciencecareers.org/job/674888/f...
Come and work with us 5-year position available for a University Researcher in Bioimaging 1.11.2025-31.12.2030 abo.rekrytointi.com/paikat/index...
Watch @maxgg.bsky.social, Group Leader at the Crick, as he explains what happens to cells that are infected with tuberculosis and how his lab is studying our bodies’ response to this infection. www.youtube.com/watch?v=VWCt...
Finally, a way to save posts that doesn't involve that thumbtack emoji!
(1) In my experience, when data management doesn't happen until the end of a project, about 80% of DM is detective work (what are these values, why is data missing, how do we handle this messy data)? This way of working is tedious, often frustrating, and can lead to lost or misunderstood data.
They need to do a better job of framing their arguments now to shape public opinion in their favor or this is another battle they'll lose.
#Microsky 🦠 🧪
Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival
If you're a reporter, please stop referring to RFK Jr and his cronies as "vaccine skeptics." They're not skeptical. Skepticism would be fine. Skeptics look at evidence and can be persuaded. These people are extremist anti-vaccine cranks, and that's how news organizations should describe them.
Cholera is making a comeback in the Africa region www.npr.org/sections/goa...
Postdoc advertisement! Hi all, I'm looking to hire a Postdoc in BIOACOUSTICS for work on Owls. Your job would be to collect & analyze bioacoustics data, and write papers. 🦉🦉🦅🐦🦜🦉🦉
Great advice!
Today’s enthusiasm for targeting BAT is exemplified Neuritin-1 which emerges as a potential target for the treatment of metabolic disorders. www.nature.com/articles/s41...
As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Read our statement: asm.org/press-releas...
For those of you in New York! • www.wcvb.com/article/stat... And for those of you in Washington, Oregon, and California! • www.reuters.com/business/hea...
For those of you in Colorado! coloradosun.com/2025/09/03/c... Colorado has issued orders that allows EVERYONE 6 months and older to be able to get a COVID vaccine this year WITHOUT a prescription.
Really cool work, which supports our previous works on Anopheles' microbiome, immune response and activation through age and its links to "metabolic reprogramming" - one of my favourite things www.biorxiv.org/content/10.1...
COVID VACCINE INFO: List of states requiring a prescription for a COVID vaccine at CVS or Walgreens t.co/ZqCZwxwa57 COVID vaccine availability at CVS buff.ly/JHG5vml 💉COVID vaccines are no longer available at CVS in Massachusetts, Nevada or New Mexico. Vaccines.gov is still down. #medsky 🛟😷🧪
An extraordinary joint op-ed and plea by NINE former directors or acting directors of the CDC under both Democratic and Republican administrations, succinctly describing undermining of public health, and what’s needed now. (gift link) www.nytimes.com/2025/09/01/o...
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions. Descriptions and links in the following two posts.
Excited to announce a search for an Associate or Full Professor in Infectious Disease Modeling at Penn State's Center for Infectious Disease Dynamics. Details at link and below. psu.wd1.myworkdayjobs.com/en-US/PSU_Ac...
9 CDC Directors going back to 1977 speak out. What RFK Jr has done to our nation’s public health system "should alarm every American." It "is unlike anything we have ever seen at the agency, and unlike anything our country has ever experienced." www.nytimes.com/2025/09/01/o...
📢📢Hiring 2 Research Assistants & 2 Postdocs at Emory University in Atlanta to study cytoskeletal biophysics/biochemistry. Please RT. RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to shekhar@emory.edu. More info: www.shekharlab.org
I am chairing the search for two (2) Tenure Track positions at the Department of Health Services, Policy and Management at @uscarnoldschool.bsky.social We are looking to move relatively fast so please get your applications in quickly #HealthPolicy #AcademicSky uscjobs.sc.edu/postings/194...
Ancient Origins and Global Diversity of Plague: Genomic Evidence for Deep Eurasian Reservoirs and Recurrent Emergence mdpi.com/3442038 #mdpipathogens
The Republican Congress is going to try to rewrite the history of RFK Jr.’s confirmation as HHS Secretary. “We didn’t know” “Nobody told us” “He promised he wouldn’t…” This thread will be about the warnings from thousands of scientists and HCW who loudly and publicly opposed his confirmation.
A public health catastrophe. Not “immanent,” not “potential.” This is the catastrophe.
If you’re in Louisiana and eligible for a COVID shot, CVS won’t give them at all. They’re cowards. But Walgreens will. I have mine scheduled for next week.
#InterferonPower! Thrilled for our latest work @cp-cell.bsky.social! With @danielboehmer.bsky.social, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IV😉) #interferons! Free👉 authors.elsevier.com/a/1leKGL7PXu...
Our study developing a skin metatranscriptomics protocol is now out in @natbiotech.nature.com! We finally have the ability to study microbial activity on skin and identify key functional genes playing a role in diseases. Amazing team of Chia Minghao and Amanda Ng 👏 nature.com/articles/s41...
This comment says all you need to know about Noem's management style: "Noem devoted nine paragraphs of her statement about the breach to attacks on FEMA's IT staff, accusing them of "failure," "neglect," "incompetence" and dishonesty. She said 23 of them had been fired."
Which antibody, kit, or instrument worked best in your lab? Share your experience in a Biocompare Product Review. Your insights guide other scientists and give you a chance to win one of five $100 Amazon Gift Cards each month. Write a review: www.biocompare.com/start-your-r...
NEW: Don't ask too many questions, but... NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all. To the PIs of reinstated grants, SPEND NOW! 🧵 Here's what NIH is probably thinking. Bear with me:
Three postdoc positions are now open for applications! Live and work on Kaurna land (Adelaide) in sunny South Australia. We have beach views, wineries, kangaroos, and koalas. Develop new synthetic biology to engineer and understand #phage, and computational tools for #phage and #microbiome analysis
Just a heads up. I was able to schedule my COVID vaccine appointment. Online it will ask “do you have a condition that puts you at high risk for severe outcomes from COVID-19 virus.” Click yes and it will allow you to schedule an appointment. No questions asked. No proof required. Pass it on.
Faculty opening in Cornell Chemistry at the Assistant Professor level in the area of chemical biology, broadly defined! academicjobsonline.org/ajo/jobs/30338 #chemjobs
🚨🧵My latest: As measles took off in Texas, the Trump administration took actions that prevented CDC scientists from responding. The outbreak became the biggest in 30 yrs. It’s far larger considering the outbreaks it sparked in other states & Mexico. kffhealthnews.org/news/article...
Studies indicate that the benefits of mRNA vaccines outweigh the risks. The pandemic might seem like a distant memory to some, but we must never, ever, forget that millions are alive today, or in better health, because of this life-saving technology. 🔗 Nature editorial www.nature.com/articles/d41...
Collective cell motion has many forms, but rotation is the coolest of them all. I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab
Extreme weather events can be complicated by the emergence of unusual infectious diseases (see "Disaster Microbiology" by Smith & Casadevall. mBio, 2022). This article links two US cases of melioidosis to Hurricane Helene. arstechnica.com/health/2025/...
Our Pitt Microbiology and Molecular Genetics department in the School of Medicine is recruiting.. Microbiologists! 🧫🦠🔬🧪 Please apply to join our faculty and enjoy these views 👀 while doing great science cfopitt.taleo.net/careersectio...
Health departments struggle to adequately survey for ticks to warn doctors about new species and the diseases they carry.
🧐 #tuberculosis #IDSky #MedSky #PublicHealth
A friendly reminder that the NIH Public Access Policy IS NOT “you must publish open access” but rather “you must ensure your copy of your paper is deposited into PubMed Central.” Yes, it is very confusing. Yes, you should be able to do that deposit yourself without paying anything to a journal.
Postdoc opportunity with @tomasbruna.bsky.social here at @jgi.doe.gov @berkeleylab.lbl.gov: Develop, benchmark, and apply Plant Genomic Language Models (gLMs) 🌿🧬💻 jobs.lbl.gov/jobs/computa... #AI #PlantGenomics #gLMs #Postdoc
“The daily cost of the D.C. troop deployment is more than six times what it would cost to operate affordable housing for D.C.’s entire unhoused population. The government’s priorities could not be more clear," said @hannahomestead.bsky.social of @nationalpriorities.bsky.social
Look at 'em go!
Let them know you're filming them and keep asking the key questions: "Do you have a warrant signed by a judge? Show me." "Do you have a badge? Show me." "Do you know how pathetic you are? You showed me."
Vaccine panel fired by Kennedy had lowest rate of financial conflicts since 2000, study shows reut.rs/45EsXbM
For those recalling the awesome session on ecology and evolution of zoonoses at GRC MPB 2023, or those who wish they were there, these authors and topic were on Rosie's and my wish list. Ancient pathogen genomes have much to say. www.cell.com/cell/fulltex...
The mad king gets madder.
An open W2 Professorship position in Molecular Crop Improvement at my Institute @uni-muenster.de! Excellent scientific environment and great conditions for Plant Research 🔬🍅🫛🥒🌽🍓🍎🥔- now open for applications !
ICYMI: Mapping the quiet development of a “silent killer.” Neeha Zaidi & team present in-depth spatial characterization of early precancer lesions in pancreatic cancer (PDAC), noting the organization of lymphoid cells: buff.ly/686Hz5G
Just a reminder that you are not the boss. Your cat is the boss. 😂
Federal court refuses to block Alabama’s “divisive concepts” law, says university faculty classroom speech is government speech with no First Amendment protection. This dangerous development allows lawmakers to dictate what professors say in class. storage.courtlistener.com/recap/gov.us...
trypanosoma parasites before/after expansion microscopy from neighbor lab. having fun at the institute @izb-unibern.bsky.social ! (btw there is an open assist. prof position - can def. recommend if you enjoy late night recreational microscopy)
We need BOOKMARKS!
www.nature.com/articles/s41...
Protein markers like Ki-67 offer a rapid, direct, and reliable way to assess cell proliferation in 2D and 3D cultures. Learn the benefits of using protein markers for studying cell proliferation and explore how these can be applied in your research. Read here: www.biocompare.com/Editorial-Ar...
Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neutrophils, cancer, and cardiovascular disease", just published @jem.org with Saira Ambreen, Afshan McCarthy and @drusqui.bsky.social rupress.org/jem/article/...
The new vision for America's future: a diminished pipeline of research labs supporting a diminished innovation economy impacting communities all across the United States, new from @carolynyjohnson.bsky.social from @washingtonpost.com: 🎁 link: wapo.st/3HreGqA
Can we use what we’ve learned so far about #immunometabolism in macrophages and neutrophils as cancer immunotherapy? Not yet, but someday. I’m happy to share our latest review, summarizing the state of the field in the context of #myeloidcells and #lungcancer www.sciencedirect.com/science/arti...