It's not a diet drug. This is a common misconception. GLP-1's have actually been around for a decade or so--they were developed to treat diabetes and prediabetes, and were originally used at lower doses (1.0mg/week as the top dose, iirc). Doctors noticed, however, that people on it were losing--
Yes it was originally developed for diabetes but it is a diet drug. The main way it helps people lose weight is by preventing overeating through appetite suppression, from everything I've read. It does it without stimulants sure, but it still does basically the same thing.
No, that's not an accurate understanding of how the drug works. Like, not at all. When you eat, your body releases a hormone called GLP-1 from your gut. This is the hormone that the body naturally produces when it's been satiated. GLP-1 has a lot of effects throughout the body, but one of them--
That's a (poor and inaccurate) plain language explainer. www.drugs.com/medical-answ...
This is just a longer way of saying the other two things I said plus a few other things
.......... No, it really isn't. It's saying exactly what I've been saying since my first Post's that it's a drug that does a shitload of things, *one of which happens to be* weight loss But whatever. You're dug in on your misunderstanding, and you can chill there. 🤷♀️
--is to tell other parts of your gut to stop producing ghrelin, the hormone that tells your body to seek food and makes you feel hungry, for a while. GLP-1 drugs like Wegovy, as you've probably noticed by now, are just a long-acting version of the hormone your body produces by itself.
To put it a different way: Wegovy it the estradiol valerate to the human body's estradiol. Same stuff, just lasts longer.
--weight at healthy rates and keeping it off, so the manufacturer ran some trials at higher doses to see how safety played out. That's the story of how Wegovy came to be. The reason for all this is that GLP-1's are hormone-affecting drugs, and the thing with hormones is they they have MASSIVE--
--effects at every level of the body, kind of like how HRT can totally reshape the entire body off of a few milligrams of hormones a day. I'm normally very skeptical of this sorta thing too, but we have almost twenty years of safety data now. If something was gonna pop up, it would've by now.
I don't necessarily think it's dangerous, I just think when people start claiming a popular weight loss medication is a panacea it almost never turns out to be true.
First of all: I did lead with "if confirmed." And second of all: its not a weight loss drug. It just happens to do that. You seem really hung up on that part.
We are specifically talking about the glp-1 drugs developed for weight loss as per the article you shared.
You have a fundamental misunderstanding of GLP-1 medicine despite having been corrected already
Corrected by a technical writer. If a person who studies pharmaceuticals tells me I'm way off base maybe I'll adjust, but I'm going to go off of what a literal medical text said instead. Which is the drug helps with weight loss through appetite suppression and delayed emptying of the stomach.
Thanks for the backhanded insult and the dismissal of my *checks notes* doctorate in technical communications with a specialty in biomedical communications and my *checks notes again* literal years of experience teaching pharmaceutical grad students how to do research writing.
They weren’t developed for weight loss, it’s literally the same diabetic medication that existed for ages just re-branded for weight loss. It’s the same pharmaceutical.
It's the same chemical at a dose that is specifically intended to help people lose weight by making it take longer for their stomach to empty and by suppressing appetite. Those are the side effects of the diabetic medication that help with weight loss.