By harm, I mean physical or mental distress to humans, destroying biological ecosystems, or forcing subjects to go through painful/stressful situations (like physical pain or spreading disease). IDK what you mean by the second one. I'm also out of space.
How would you define physical or mental distress? Can a surgeon cut you up to try and fix an issue? Can you confront a friend to set a boundary? What counts as a biological ecosystem, the Amazon or is it immoral to destroy billions of organisms with disinfectant spray?