The KP.2 variant and the JN.1 variant are very similar, and in their data they showed no evidence of an antibody response against KP.2 despite a solid one against JN.1. These differ from one another very minimally so the result didn't make sense. They labeled it "ND" on their slides...
which usually means not detected, i.e., they could not get evidence of an antibody response. In an updated version of the slides they clarified it meant "not done" because mice can only give you so much blood to use for testing.
So you feel okay with the novavax vaccine data?
Yes, once they clarified it's fine. If mRNA is a tough time for people, Novavax would be much better than no vaccine.
You’d still choose the mRNA over novavax for the next booster?
I have no meaningful reactogenicity after my mRNA vaccine doses (all Pfizer/BioNTech so far), and the CD8 T cell responses are clearly superior, which could become important if there is a massive antigenic saltation event.
I really, really wish I could just get mRNA-1083 already though. I am so annoyed that it was delayed for absolutely no good reason.
The flu/covid combo?
Yeah
Again, thank you so much. I learned a lot!