Is actually the opposite. It accelerates vitals if anything. It primarily works NMDA pathway and comparing to opioids is nonsensical unless you do molecular pharmacology for a living and can speak to the nuances
Replies
Isn't ketamine what killed Matthew Perry?
dec 30, 2024, 4:23 am • 4 0 • view
It is, at least contributed. But mainly because he was in a hot tub and became so sedated that he drowned. If he took the exact same dose on his couch, he would’ve been fine
dec 30, 2024, 4:48 am • 3 0 • view
How long til Elon’s mind deteriorates so bad that he’ll collapse into a toothless and quivering junkie who can no longer hide his moral & intellectual fraudulence from the world. (Apologies to the junkies not named Elon.)
dec 30, 2024, 7:51 am • 4 0 • view
Elon Musk is already cracking. ICYMI see screenshot from Twitter below:
dec 30, 2024, 8:56 am • 1 0 • view
Apparently, Trump has been decompensating for well over a year (a different form of deterioration admittedly) but the public can’t tell. I’m hoping drugs speeds Elon’s along.
dec 30, 2024, 9:05 am • 3 0 • view
Actually,my 18 year old daughter died from Neuroendocrine Pancreatic and liver cancer after fighting it for 2 years. Her palliative care hemo-onc doctor explained it to us in the way I said...when we discussed end of life pain management. Living it vs reading about it
dec 30, 2024, 3:02 am • 41 1 • view
I'm so sorry. 💔
dec 30, 2024, 3:37 am • 2 0 • view
I’m deeply sorry for your family’s loss. ❤️🩹🕊️🤍
dec 30, 2024, 5:20 am • 2 0 • view
I’m so sorry for your loss. :(
dec 30, 2024, 4:04 am • 2 0 • view
So sorry for your loss. May her memory be a blessing.
dec 30, 2024, 5:32 am • 2 0 • view
So sorry for your loss. And thank you for talking through this. It no doubt is very painful.
dec 30, 2024, 4:51 am • 2 0 • view
I am so sorry for your loss. 😓 I hope you have a strong system of support in dealing with this tragedy. May your daughter’s memory be for a blessing. 💔🕯️
dec 30, 2024, 7:35 am • 2 0 • view
I'm fairly certain he claims to "microdose" which is done with lots of things that would render one useless at full strength. (THC, psylocybin, LSD) He fancies himself a brinksman.
dec 30, 2024, 3:16 am • 5 0 • view
Well, we know what happened to Prince, Elvis, and many others.. Adding more, more, mistakes in dosing, who knows... Dangerous especially mixing with his other drugs
dec 30, 2024, 10:39 am • 1 0 • view
I’m very sorry for your loss. I specialize in that kind of cancer, coincidentally. The way they explained it to you is not correct.
dec 30, 2024, 3:05 am • 62 0 • view
Also sorry for your loss. Anesthesiologist here, but iruntbamimma is correct. Although it has potent analgesic properties, Ketamine acts primarily on NMDA receptors, not opiate receptors. It is hallucinogenic, differing in chemical structure from LSD by a single methyl group.
dec 30, 2024, 3:20 am • 107 4 • view
LSD & Ketamine don’t have similar structures at all
dec 30, 2024, 5:23 am • 4 0 • view
I’d just like to say that I love all of the educated people here. In the last years of Twitter, I longed to see this kind of intelligent banter.
dec 30, 2024, 3:57 am • 162 1 • view
Yesss, nice...
dec 30, 2024, 10:42 am • 2 0 • view
It's not just banter but intelligent and thoughtful conversation that some of us definitely appreciate very much. So thank you all.
dec 30, 2024, 5:52 am • 42 0 • view
Agree... Think we try.. Add a little humorous relief every now and then Here to share, support, learn... Etc
dec 30, 2024, 10:44 am • 3 0 • view
Appreciate your post
dec 30, 2024, 3:59 am • 4 0 • view
Isn’t ketamine used in pediatric surgery as ‘light’ anesthesia?
dec 30, 2024, 3:26 am • 2 0 • view
Not just pediatric. Ketamine and propofol are used commonly for procedural sedation.
dec 30, 2024, 3:32 am • 10 0 • view
👍
dec 30, 2024, 3:35 am • 0 0 • view
Indeed, a wonderful ride (that killed Micheal Jackson?) ;)
dec 30, 2024, 9:23 pm • 0 0 • view
I wouldn’t say it’s for “light” anesthesia, but there are reasons to use it. Someone may have told you that because you can administer ketamine and patients will tolerate noxious stimuli but continue to breathe, thus appearing to be “lightly” anesthetized.
dec 30, 2024, 3:39 am • 4 0 • view
With that said, it still requires careful monitoring by qualified people. As Matthew Perry recently demonstrated.
dec 30, 2024, 3:40 am • 4 0 • view
And I guess I should have added that I’m pretty sure that in ‘normal’ times anyone being treated with ketamine would face significant scrutiny during a federal security clearance audit. Anyone exhibiting signs of dependency would have to fail said audit. Not sure that these are normal times.
dec 30, 2024, 3:48 am • 2 0 • view
Used on my toddler son to help place a PICC. I was in the room. He was o u t 😂 He’s doing great in grad school now.
dec 30, 2024, 3:44 am • 2 0 • view
Thank you. Why is it used for end stage cancer? I sat with her that last day, and she did not seem to be in pain; my assumption was that it was the ketamine IV drip.
dec 30, 2024, 3:25 am • 4 0 • view
As I said, it is a potent analgesic and is sometimes clinically useful, especially for people who have been in chronic pain, who may have become habituated to opiates, such that opiates no longer provide adequate pain relief.
dec 30, 2024, 3:30 am • 10 0 • view
Again, that makes sense. Who knows what i heard or believed i heard. As you can imagine, it was a brutal battle and we just wanted her comfortable. Thank you for clarification.
dec 30, 2024, 3:35 am • 8 0 • view
This is the kind of interaction I’m here for. Thank you for continuing to ask and not shutting things down. And very sorry for your loss. A parent shouldn’t outlive their children. Love and hugs.
dec 30, 2024, 4:07 am • 3 0 • view
My heart goes out to you ❤️We are working on better treatments. big picture her docs were right that ketamine is brought out when usual opioid regimens aren’t cutting it anymore. It’s probably “safer” drug in that it’s harder to OD, but oft requires IV and more expertise. So, it’s “beyond” opioids
dec 30, 2024, 4:53 am • 2 0 • view
I cannot even imagine what it is to sit by the bedside of your child and see them suffer. It would be near-impossible to absorb everything you were told under those circumstances.
dec 30, 2024, 3:43 am • 5 0 • view
❤️🩹
dec 30, 2024, 5:35 am • 1 0 • view
What you've lived is unthinkable to just about anybody reading your comment. I am incredibly saddened. I'm certain your daughter was fiercely courageous.
dec 30, 2024, 3:23 am • 6 0 • view
How terrible. I’m so sorry about your daughter. Heartbreaking
dec 30, 2024, 3:13 am • 5 0 • view
It is. Thank you.
dec 30, 2024, 3:26 am • 2 0 • view
I'm so sorry for your loss. Seeing a child in such pain is a tragedy. Whatever helped her on her last days was welcomed.
dec 30, 2024, 8:52 am • 3 0 • view