Thinking about fibromyalgia. It's apparently more commonly diagnosed in women than men. Why, unclear. Someone I inbox said their sister actually had it improve as they got older. Is it one of these more unusual conditions that is both more rare & truly worse for males? Suggests X chromosome relevant
My fibromyalgia, diagnosed in 2006, after a nasty norovirus, has gotten worse as I have aged. It has ruined my career as an RN & my quality of life. Each day is a struggle… You never know how bad of a Fibro day it will be, until you open your eyes every morning. Eehhhhh
Sorry to hear. Mine's especially bad at the moment after I've burned through my reserves with an intense self-detox & I'm not doing myself any favours with smoking rollups, drinking lots of coffee & all too frequently a lot of beer when I can't cope with the stupefying misery of the fatigue. Horrid.
I hear you. I’m also sorry to hear of your current situation. It can be hard to not burn through your reserves. Please stay strong and be as “well” as you can. Gentle hugs to you
Thanks. I'm glad anyone gets it, horrible as it is. So I really am trying my best to sort it out but my brain has decided I'm going to be all of ASD, ADHD, Bipolar 1, possibly schizo-affective. I'm a credit to myself I'm as functional as I am but I'm starting to think I need carers or a cleaner now🤦🏻♂️
Completely relatable
So to build on my earlier hypothesis I put together with help from someone who knows biomedical science: Persistent Extreme Stress by itself nvm polluting your body in response, maybe causes RNA changes to an X chromosome as well as mitochondria. Weakened muscles & connective tissues simultaneously
The X chromosome, through its immune-related genes influences gut microbiome composition, but there is no current evidence that it promotes gut microbiota which are intrinsically more prone to generating reactive oxygen species. 1/
The role of gut microbiota in ROS and redox balance is well-supported, but causality specifically tied to X-chromosomal genetic differences remains unexplored. Nevertheless, antioxidants like hydrogen rich water that neutralize ROS have helped a few of my FM clients reduce inflammation. 2/
I wish I was qualified or at least knowledgeable enough to speak to you about this properly. I get the approximate gist of what you're saying here. I'm just glad it appears medical science is starting to get somewhere understanding this horribly nasty ailment. In my case I'm trying to live healthier
As for me personally I'm a bit stuck. Lack of exercise for months has left me stuck with getting post-exertional malaise from even a ten minute walk. The hour round trip to the shops about a week ago has absolutely done me in I reckon. So immediately worse from exercise. More rest = muscle atrophy🤷🏻♂️🤦🏻♂️
What does "I inbox" mean please?
People I exchange Direct Messages with
Ooooo