I’ve been in those worlds enough to be familiar with what you’re talking about, and even considered some of these tests myself, but I wonder, did any of these commercial gene testing stuff actually change what you did, and your outcomes?
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I did the ancestry test nearly 10 years ago and used promethease. I changed how I took b vitamins (methylcobalmin, etc) and increased choline intake and tapered off my snri. Since then I noticed I was responding weirdly to b vits and went back to Reddit, found new online tools and there's...
jun 22, 2025, 2:49 pm • 0 0 • view
...been more research into MTHFR. I think covid messed up my microbiome or did something funky epigenetic wise because I can't do methylcobalmin anymore and had to taper up separate b vits (hydroxycobalmin, etc) slowly. I don't know any drs in Ireland who would have been able to help with this.
jun 22, 2025, 2:52 pm • 0 0 • view
There may be other things at play too. Once I fixed one vitamin, another deficiency showed up. Sometimes it's because these things work together.
jun 22, 2025, 3:26 pm • 1 0 • view
Covid messes up vitamins for sure. It depletes A and Thiamine. There is also something called methyl trapping. Not everyone does well with methylated vitamins. MAOA gene. Natural folate in leafy greens is helpful. I have MTHFR too. But there are a few genes that deal with that MTRR and MTR also.
jun 22, 2025, 3:13 pm • 2 0 • view
The leafy greens part might explain why my body is picky about them now. I can't eat Pak choi amongst other veg. Vit A is 1 that came up with the genes as I don't process beta carotene very well. Need to look into methyl trapping. Thanks
jun 22, 2025, 3:35 pm • 0 0 • view
I can't remember my exact profile just what is recommended and that I'm an over methylator. Supplements that used to be fine I'm now very sensitive to (like glycine/tmg). The MTR and other genes were some of the info that was new to me when I went back onto the subreddits.
jun 22, 2025, 3:39 pm • 0 0 • view
Glycine lowers serotonin. It's a true journey because you may not notice something until you fix a different problem. When I took methyl folate and depression went away, anxiety took its place. Now that I can make serotonin, I found out I have trouble getting rid of it due to another snp.
jun 22, 2025, 3:49 pm • 1 0 • view
It's also supposed to help release methyl groups (maybe that's how it lowers serotonin?) so MTHFR people take it to help with over methylation (fwiu). I wonder how your gut microbiome is given that's where b12 triggers 5htp ->seratonin? There's probably a probiotic strain that would really suit you
jun 22, 2025, 7:42 pm • 0 0 • view
Probiotics are key. There is a gene for FUT2 that determines if your gut is a good host for certain microbes. Companies can now test you for a GI map. Like the other test it gives you good answers as to what mix of probiotics is best. What is also interesting is the gene for anorexia.
jun 22, 2025, 9:38 pm • 1 0 • view
The serotonin transport genes. Serotonin in excess makes folks anxious. Not warm & fuzzy like most folks. If you have too much serotonin you feel better when you don't eat. If you eat a high carb meal, your serotonin will go even higher. I often wonder if keto will help anorexics with those genes.
jun 22, 2025, 9:38 pm • 1 0 • view
There are so many variables. Oxalates are also something to consider. They can cause troubles too...
jun 22, 2025, 3:39 pm • 1 0 • view
I seem to handle those well but I'll keep an eye on it because everything changes now.
jun 22, 2025, 3:45 pm • 0 0 • view
True, you have to make small changes, and really pay attention to how you feel. The thing I learned the hard way is everyone truly is different.
jun 22, 2025, 3:52 pm • 1 0 • view
There are also herbs that help the body increase production of some things or slow down some things. I studied food science at Rutgers worked in R&D at big food companies. I thought I knew it all. Getting hit with deficiencies when I was eating right was a humbling experience. The learning curve
jun 22, 2025, 3:13 pm • 2 0 • view
That's so interesting. I had to stop being vegetarian after covid. Covid is a hell of a curve ball no matter the bat anyone is using. I'll have to look into herbs. I had heard great things about tollovid which I believe is derived from a herb used in TCM.
jun 22, 2025, 3:42 pm • 0 0 • view
On this genetics thing is steep but it is where we need to go to get to healthier folks. One mans good is def another mans poison. One size fits all nutrition has had its day. Medications that deplete vitamins need to be seriously looked at too. pmc.ncbi.nlm.nih.gov/articles/PMC...
jun 22, 2025, 3:13 pm • 2 0 • view
I meant to say one man's food 🙃
jun 22, 2025, 3:31 pm • 1 0 • view
Good still made sense.
jun 22, 2025, 3:43 pm • 1 0 • view
Yes. The test was not covered by insurance but it cost less than $400. The data goes right to your Dr. I pay about 100 per hour to talk to the counselor. That isn't covered by insurance. The cost is in the blood work tests for vitamin deficiency. That is usually covered by insurance.
jun 22, 2025, 2:31 pm • 0 0 • view