It’s not efficacy per pound, it’s whether or not people can afford £300 a month or can only pay half of that. Plus, ChatGPT isn’t exactly a reliable source.
Replies
A surprisingly good response from ChatGPT on whether it's a good source. I suspect engineered in.
sep 2, 2025, 5:34 am • 0 0 • view
I was using ChatGPT 5 subscription thinking mode - it took 3 minutes to analyse. Put another way: You would have to use wegovy for 18 months to lose the same weight as on mounjaro for 12 months So the total cost is 16% more with wegovy. Switching is a false economy (and it delays health benefits)
sep 2, 2025, 7:08 am • 0 0 • view
Again, the speed at which I lose weight is immaterial. But the 7.5mg dose of Mounjaro I’m on is now £244.99, which compares with about £128 for Wegovy 1mg. Speed of loss here is completely irrelevant when you cannot afford £250/£300 a month.
sep 2, 2025, 7:17 am • 1 0 • view
Wegovy 1.7mg would be the more appropriate price comparison at £150 It is about half as effective.
sep 2, 2025, 7:28 am • 0 0 • view
Rather than using ChatGPT to integrate two separate studies (which is dodgy practice), why not use an actual direct comparison? www.nejm.org/doi/full/10....
sep 2, 2025, 7:49 am • 0 0 • view
I am an introducing an engineering component to the science here. That is the cost effectiveness based upon the new prices announced 2 days ago.
sep 2, 2025, 8:40 am • 0 0 • view
But whatever comparison on effectiveness also needs to have a good measure of comparison. Separate studies in different populations with different inclusion requirements can’t simply be compared. Better to have direct comparisons.
sep 2, 2025, 8:43 am • 0 0 • view
Unfortunately, I cannot read that article. It is behind a paywall. Can you provide me with a link to the whole article?
sep 2, 2025, 8:47 am • 0 0 • view
on.ft.com/47SKDmA Eli Lilly raises UK price of obesity drug by up to 170% after Trump ‘freeloading’ gripe
sep 2, 2025, 8:52 am • 0 0 • view
I can gift it.
sep 2, 2025, 8:50 am • 0 0 • view
I actually used “gift” as a verb. OMG!
sep 2, 2025, 8:53 am • 0 0 • view
Or this one: jamanetwork.com/journals/jam...
sep 2, 2025, 7:50 am • 0 0 • view
Sure, if you don’t question the reliability of trials conducted by the company producing the product (see below). I think we would want to see many more independent trials before we could be confident in your projections.
sep 2, 2025, 7:20 am • 1 0 • view
Also, most of us are not that fussed if we lose weight slightly faster. I’ve lost 30% of my body weight in a year and now have a BMI of 26. I’m not sure why people think I need to lose weight much more rapidly.
sep 2, 2025, 7:24 am • 0 0 • view
In which case you should be most interested in titrating down your dose so as to hit your target BMI and then maintain it. You should be talking to your pharmacist about reducing your dose as you get near to your target weight. There is no clinical trial on this - a big problem.
sep 2, 2025, 7:31 am • 0 0 • view
Who is going to find the hundreds of millions of pounds to carry out speculative trials on drugs that may or may not work? We work within a capitalist system which is producing amazing but expensive drugs.
sep 2, 2025, 7:33 am • 0 0 • view
But that’s a different point. You’re making very concrete claims about the benefits of Mnjro over Wegovy, based on a single trial managed by the producer of your favoured drug. I would wait a bit.
sep 2, 2025, 7:51 am • 0 0 • view
Wegovy is not half the price of Mounjaro. It is about 30% less cost, but about half as effective.
sep 2, 2025, 7:13 am • 0 0 • view