Persecuting someone based on their personal choices or changes they make in their lives is an infringement on their rights. Medical journals and peer reviews have come out stating the brain chemistry of a trans man more closely aligns with that of those born as men and the same for women.
That's a mixture of issues, none of which answers my question. I'm happy to discuss them individually, but only if you can at least agree that there are rational societal limits to personal freedoms. I'm hardly asking for the moon, just a basic ethical benchmark.
If someone's right to safety or life is violated by someone else, then I'd agree that is a basis for dispute.