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Dr. John Wagner

@drjohnwagner.bsky.social

Proud dad. Applied mathematician. Life scientist. Consummate inventor. Software engineer. Data nerd. Life-long foodie. Aspiring chef. Progressive lefty taking refuge in a blue state with blue skies. #CT #Bsky

created November 13, 2024

1,569 followers 950 following 857 posts

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Posts

Profile picture George Takei (@georgetakei.bsky.social) reposted

Gotta hand it to the artist.

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30/8/2025, 7:55:46 PM | 6881 1017 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

I don't know whether Penn State or Ohio State should have been ranked #1, but I know it shouldn't have been Texas. Texas football--both the state and the school--are totally overrated. One national championship in the last 50+ years, right?

30/8/2025, 8:33:49 PM | 0 0 | View on Bluesky | view

Profile picture Colin Carlson (@colincarlson.bsky.social) reposted

With O'Neill (apparently) taking over CDC (if they ever get around to firing Monarez), I think it's worth looking back to Project 2025 and asking what they actually intend to *do* to CDC. So, I went to remind myself today. Here's what's in store:

29/8/2025, 8:56:31 PM | 1290 671 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

I'm game.

30/8/2025, 8:48:16 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

LOL Who could blame her?

30/8/2025, 8:47:43 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

'Xactly.

30/8/2025, 6:34:18 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

Can confirm.

30/8/2025, 6:26:05 AM | 2 0 | View on Bluesky | view

Profile picture Siân Owen (@sianowen.bsky.social) reposted

An inspiring read! academic.oup.com/genetics/adv... A beautiful historical perspective on Ester Lederberg's legacy from @ccwendling.bsky.social & @zacharybailey.bsky.social

28/8/2025, 10:52:46 PM | 45 25 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

I lived in Melbourne from 2010 to 2021. I'm with you.

29/8/2025, 10:06:00 AM | 1 0 | View on Bluesky | view

Profile picture luke steuber (@lukesteuber.com) reposted reply parent

This one is just sad

There were other naturalized citizens among the applicants. Farzana Pramanik, 38, who was born in Bangladesh and wore a head covering, told me she had no law-enforcement background, but speaks Bengali, and some Hindi, and said she thought she could help people in ICE custody who know only those languages.
29/8/2025, 8:53:23 AM | 33 4 | View on Bluesky | view

Profile picture Aparna Nair (@disabilitystor1.bsky.social) reposted

oh goddess, Jesus, and every deity on the planet You know what, I don't care if her colleagues to be treat her badly. Which the fascists absolutely will. You can't girlboss fascism. Zero sympathy. ZERO. Work for ICE. And get what you deserve.

29/8/2025, 9:00:23 AM | 18 5 | View on Bluesky | view

Profile picture Wild Colonial Girl is sick of rich idiots trashing our world 🔥 (@colonialgirl.bsky.social) reposted

@albomp.bsky.social When can we expect our Special Envoy to Combat Antisemitism to show up and combat these antisemites? Will she be combating them in person or will she be fighting through the courts to stop their antisemitic march from going ahead? What is Jillian Segal paid for if not this?

29/8/2025, 6:28:27 AM | 169 61 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

It will keep over and over and over again until Americans finally understans that guns do not equal safety plus freedom.

29/8/2025, 9:01:51 AM | 1 0 | View on Bluesky | view

Profile picture leftynavyseal.bsky.social (@leftynavyseal.bsky.social) reposted

Scientific American: For 20 years, Denmark conducted a large and meticulous study of whether aluminum in vaccines caused chronic childhood diseases. The data was clear: It did not. Malignant crackpot RDK Jr wanted a retraction of the study. The Annals of Internal Medicine said no.

28/8/2025, 12:31:14 PM | 1672 483 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

If “The right in this bill is an aspiration, and doesn’t give us any ability to do any more than what we are currently doing" then there is no point to the bill other than to normalise guns. Or for Minns to drum up support for another unpopular bill.

29/8/2025, 5:47:11 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Yeah, "however unlikely" is definitely relative. At this point it's likelier than shit.

29/8/2025, 5:21:26 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

I think so. It's not the most in-depth article I've read.

29/8/2025, 5:18:25 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

LOL No you wouldn't.

29/8/2025, 4:47:59 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Don't threaten me with a good time...

29/8/2025, 2:48:37 AM | 3 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Word.

29/8/2025, 2:46:09 AM | 2 0 | View on Bluesky | view

Profile picture Esthiru 🏳️‍⚧️ (@esthiru.bsky.social) reposted reply parent

Remember: Be the Luigi Mangione you want to see in the world.

28/8/2025, 10:47:13 PM | 18 3 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

They included "the diagnosis and treatment of impotence" so this will go nowhere. LOLOL

29/8/2025, 2:43:43 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

We're going to need a whole helluva lot more Luigis.

29/8/2025, 2:40:44 AM | 2 1 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

💯

29/8/2025, 2:39:25 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

💯 It's far too late for the US. The US is far too happy to continue sacrificing school children to ever reconsider their insane view that "guns = safety and freedom".

29/8/2025, 2:19:57 AM | 1 0 | View on Bluesky | view

Profile picture Denise Wheeler (@denisedwheeler.bsky.social) reposted

The new ICE song by Jesse Welles nails it. ICE isn’t recruiting heroes, it’s recruiting the bitter, the rejected, the ones desperate for a badge to cover their failures. Losers with power become the most dangerous kind. (c/o Caroline Codsi)

29/8/2025, 12:18:30 AM | 13302 4506 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

"We will not be intimidated and we will not be silent." And yet you "went to Moshannon Valley ICE Detention Center to conduct oversight and [were] shut out." What are you going to do to resolve that contradiction?

29/8/2025, 1:34:10 AM | 11 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Agreed on all points except the supremacy of regulation. As I always point out, Peter Drucker famously said that "culture eats strategy for breakfast". Regulation is strategy. It will continue to have zero effect unless and until Americans finally change their culture of "guns = safety and freedom".

29/8/2025, 1:32:37 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

💯

29/8/2025, 1:28:08 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

One of my dearest friends is one of the most brilliant architects in Australia, and another is one of the most brilliant healthcare AI researchers in Australia. And their partners are absolutely wonderful humans.

29/8/2025, 12:44:45 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

To be clearer, the foundations in public health had been cracking for decades. This is not cracking. This is shattering.

29/8/2025, 12:09:49 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

All of the Desi women I know are amazing people with amazing partners. But I'm pretty sure my sample size is nowhere near yours. :D Also, almost all of the Desi women I know are in Australia.

28/8/2025, 11:57:58 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Not a lawyer but my guess is if someone you vaccinated against FDA guidelines had some kind of debilitating adverse reaction to the vaccine you would have a lot steeper uphill battle in court?

28/8/2025, 11:41:56 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Yeah. True dat. Kinda the opposite for me hey. I can't believe how many utterly shit human(ish) beings are in pretty much every one of my demographics.

28/8/2025, 11:34:13 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Or almost as bad, Jay Bhattacharya or Vinay Prasad.

28/8/2025, 11:24:33 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Americans love their country but fear their government. It's beyond bizarre. 🇨🇦 🇩🇪 🇨🇭 have nowhere near 🇺🇸 levels of gun ownership but even if they did, it still wouldn't be a fair comparison. 🇨🇦 🇩🇪 🇨🇭 don't sell ~4M AR-15s a year.

28/8/2025, 11:19:31 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

My kids never once practiced for the entire six years they were in secondary school. Because they went to secondary school in Australia.

27/8/2025, 7:58:55 PM | 7 3 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

This. All this.

27/8/2025, 7:54:49 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Yes. Because what you did wasn't even a strategy, it was at best a tactic. (American gun violence) culture eats (gun violence legislation) strategy for breakfast. And flosses its teeth with (gun violence legislation) tactics.

27/8/2025, 7:50:21 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

The United States of American has a gun *culture* problem predicated on the uniquely-American and unmovable belief that "guns = safety and freedom". I sent my kids to schools/universities with zero risk of school shootings. I recommend you do the same. The US is a shooting gallery with 400M+ guns.

27/8/2025, 7:46:55 PM | 2 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

It is what it is. It's simply not possible to change the uniquely-American narrative that "guns = safety and freedom". Peter Drucker famously said that "culture eats strategy for breakfast". Until and unless American culture changes no "gun safety" half-measures will have even the slightest impact.

27/8/2025, 7:37:23 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

He doesn't have a plan. Just empty words about "rallying around the Annunciation Church." Not "rallying around the idea that gun violence can and must be prevented even i̶f̶ though it means repealing the Second Amendment". Because that would require courage. And no US Senator has any of that.

27/8/2025, 7:27:38 PM | 2 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

One that Americans are incapable of.

27/8/2025, 7:22:51 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

I wasn't attempting to correct you so much as push back against the wider and deeper narrative. But like every American, I'm doing absofuckinglutely nothing about gun violence.

27/8/2025, 7:11:13 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

My plan for when he's gone? I plan to drive the truck dragging his body through the streets.

27/8/2025, 7:04:28 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

There is no "gun safety". There are guns. Or there is safety. Either or.

27/8/2025, 7:01:53 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

I think it's time to start prying them from their cold, dead hands.

27/8/2025, 6:59:00 PM | 2 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Imagine effects so large that for decades scientists couldn't find a single one of these "simple interventions" leading to a >600 fold increase in risk. For reference: smoking only increases the risk of lung cancer by about 20.

27/8/2025, 6:43:24 PM | 6 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

This was always, among other things, Musk's way of catapulting xAI to the front of "AI for Government". Imagine what a huge competitive advantage "Grok for Government" has with all of the training data Musk stole.

27/8/2025, 6:22:37 PM | 3 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

Why not also rename it the Reichsbahn while you're at it?

27/8/2025, 6:18:34 PM | 3 2 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

Give them no quarter. Susan's problem isn't that these constituents won't listen. It's that Collins doesn't listen to her constituents.

27/8/2025, 6:13:22 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

Thank gawd they're getting rid of all those damn woke airborne toxicants!

25/8/2025, 12:36:14 AM | 0 0 | View on Bluesky | view

Profile picture Karen K. Ho (@karenho.bsky.social) reposted reply parent

I just cannot imagine Cuomo or Adams getting this many people, especially people 40 and under, on a beautiful summer Sunday afternoon to do a scavenger hunts accessible by public transit

A large crowd of people waiting at union Square for scavenger hunt cards for an event organized by Zohran Mamdani's election campaign A large crowd of people waiting in five linees at union Square for scavenger hunt cards for an event organized by Zohran Mamdani's election campaign
24/8/2025, 6:10:42 PM | 2403 414 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

Has anyone else noticed how we haven't heard anything about Luigi? It's almost as if they don't want us to remember that he's a national hero who was doing the Lord's work.

24/8/2025, 11:04:57 AM | 1 1 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Definitely worth a try. Dry ice solves all travel problems.

24/8/2025, 6:05:10 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Ah. I see. Thanks.

24/8/2025, 6:04:32 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

I honestly didn't know what he was saying and what he was responding to, can you fill me in on the context? I feel like I missed something important.

24/8/2025, 4:52:54 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

"The plan is to rule like the Nazis of the 1930s and 1940s." There. Fixed it for you.

24/8/2025, 4:47:48 AM | 2 1 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Looks like it could be poisonous. You better send me some so I can test it for you.

24/8/2025, 4:45:32 AM | 2 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Yeah, he kicks the ball into his own net sometimes. But I follow him because he generally has interesting takes and viewpoints on a range of topics that, even when I disagree with, are still worth hearing and considering. Especially when he stays in his lane of expertise.

24/8/2025, 4:40:36 AM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

LOL Tom is always acting out on some level. But sometimes he's acting out for the right reasons and making a good point. I'm wondering what kind of a night tonight is. :D

24/8/2025, 4:02:39 AM | 3 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

infrastructure in the US, which we will use to produce submarines for the US.)

24/8/2025, 4:01:19 AM | 2 1 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Not only should Albo refuse to sit down with our Nazi leadership, they should also immediately withdraw from AUKUS and the utterly, hilariously stupid submarine agreement. (Australia will never, ever see those submarines, it's just a grift to get Australia to foot the bill for building submarine...

24/8/2025, 4:01:19 AM | 4 1 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Not sure what you are trying to say here?

24/8/2025, 3:57:59 AM | 2 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

It wasn't a purchase. The US isn't paying for them. It's a g̶i̶f̶t̶ vig.

23/8/2025, 6:00:03 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

That's a different exploration I've been working on very part-time.

23/8/2025, 5:57:57 AM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social)

I'd like to buy a vowel, Pat...

22/8/2025, 10:41:51 PM | 5 1 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

Trump only remembers the vig.

22/8/2025, 10:39:55 PM | 4 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

The government didn't buy the shares, so it didn't invest in Intel. It's less communism seizing the means of production and more mobster shakedown.

22/8/2025, 9:34:59 PM | 13 3 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

By targeting universities, regulatory agencies, the legal profession, and election systems, the Trump administration has weakened foundational pillars of U.S. democracy. These efforts align with historical precedents where erosion of institutional integrity preceded democratic backsliding FWIW

22/8/2025, 7:40:40 PM | 0 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

DeepSeek then concluded: These actions demonstrate a pattern of undermining institutional independence through political coercion, retaliatory measures, and erosion of checks and balances. --and--

22/8/2025, 7:40:40 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

x

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

DeepSeek responded: Based on the provided search results, here are ten examples of actions Donald Trump has taken in 2025 that undermine the strength and/or independence of U.S. institutions:

22/8/2025, 7:40:40 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

DIgging deeper on institutions, I asked DeepSeek: What are ten examples of things Donald Trump has done in 2025 to undermine the strength and/or independence of the US's institutions?

22/8/2025, 7:40:40 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

When I explicitly point to actions Trump has taken that tend to undermine these institutions, LLMs quickly back off...and end up concluding that our institutions are more moderately strong and independent.) Either way, Donald Trump is clearly doing nothing to mitigate the risk of an uprising.

22/8/2025, 7:27:09 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

(I've had dozens of deep explorations on this and related topics with several LLM, and all of them point to the strength of our institutions as strong, mitigating factors.

22/8/2025, 7:27:09 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

It also noted that historical precedents emphasise that simultaneous triggers—rather than isolated issues—are most likely to escalate into unrest.

22/8/2025, 7:27:09 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

DeepSeek then concluded that Trump's 2025 policies align closely with factors that precipitated revolutions in other countries. While the U.S. has robust institutions, these actions could amplify vulnerabilities by deepening polarisation, economic strain, and institutional distrust.

22/8/2025, 7:27:09 PM | 2 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

DeepSeek also summarised some key insights from revolutionary precedents:

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

10 Underestimate Youth Mobilization

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

9. Dismiss Cultural and Identity Grievances

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

8. Isolate the U.S. Internationally

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

7. Politicize Public Services and Civil Rights

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

6. Neglect Rural and Industrial Heartlands

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

5. Suppress Press Freedom and Digital Rights

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

4. Expand Authoritarian Security Measures

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

3. Enable Rampant Corruption and Cronyism

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

2. Ignore Economic Inequality and Youth Unemployment

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

1. Erode Democratic Institutions and Checks on Power

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Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

I then asked DeepSeek to find three examples for each item. This was not difficult. Let's look...

22/8/2025, 7:27:08 PM | 1 0 | View on Bluesky | view

Profile picture Dr. John Wagner (@drjohnwagner.bsky.social) reply parent

10. Underestimate the Power of Youth Mobilization

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