Chris Pook (@drchrispook.bsky.social) reply parent
Yes, very much agree. Whenever I engage these people I'm not doing it on the hope of changing*their* mind. I'm doing it to publicly demonstrate that their ideas are irrational and metaphysical.
Biochemistry, mass spectrometry, metabolomics, chromatography, health, nutrition, physiology, chemoinformatics, computational mass spec. Personal account. #SexMatters #SexNotGender https://thepoliticalerasureofsex.org/ https://projectnettie.wordpress.com/
344 followers 377 following 990 posts
view profile on Bluesky Chris Pook (@drchrispook.bsky.social) reply parent
Yes, very much agree. Whenever I engage these people I'm not doing it on the hope of changing*their* mind. I'm doing it to publicly demonstrate that their ideas are irrational and metaphysical.
Oliver (Oli) Jones (@drolijones.bsky.social) reposted
I am in The Sydney Morning Herald and The Age today in a great article about the #chemistry, #safety and effectiveness of #vitamins and other #supplements, the first in a six-part series by Sarah Berry. www.smh.com.au/lifestyle/he...
Chris Pook (@drchrispook.bsky.social)
Just so everyone is absolutely clear who this guy is who is encouraging people to threaten women. He is a trans-identified man who makes fetish "art" using photos of toddlers as models. He regularly visits schools, including here in NZ, to promote his "work". reduxx.info/trans-artist...
Chris Pook (@drchrispook.bsky.social) reply parent
This you, making fetish art from photos of people's kids bro? reduxx.info/trans-artist...
Lindsay K Pino (@lindsaykpino.com) reposted
Do you or your lab use the Skyline software for #MassSpectrometry #proteomics? I'm looking for instructors to help with this year's Skyline Online, a virtual workshop/crash-course for all things Skyline! I'm especially looking for early career researchers for this opportunity. Please DM!
Nikolai Slavov (@slavov-n.bsky.social) reposted
Surprising estimates about the biomass distribution on Earth: ◼️Terrestrial biomass is ~ 100-fold higher than marine biomass ◼️ Plans are mainly terrestrial, whereas animals are mainly marine ◼️ Live stock biomass exceeds human biomass
Chris Pook (@drchrispook.bsky.social)
This pretty cool. We've been mucking around with sorvennt traps and thermal desorption GC-MS. Hoping to have some funding to explore ambient and breath-born contaminants next year.
Chris Pook (@drchrispook.bsky.social) reply parent
My grandad was on them too. Would never talk about it. Too horrific.
Chris Pook (@drchrispook.bsky.social) reply parent
Thank you for sharing.
BioMassSpec (@realbiomassspec.bsky.social) reposted
Metabolomics analysis of gut metabolites in patients with colorectal polyps and in healthy individuals #ExpTherMed #MassSpec www.spandidos-publications.com/10.3892/etm....
Chris Pook (@drchrispook.bsky.social) reply parent
You are ridiculous.
Karleen Gribble (@drkarleeng.bsky.social) reposted
Today is 3 years since the paper on importance of sexed language was published. It's had 175 000 reads/downloads in 160+ countries and has an attention score in the top 0.01%. I am grateful to my coauthors who agreed to jump into the void with me! www.frontiersin.org/journals/glo...
Katie Pereira-Kotze (@katiepk.bsky.social) reposted
Really helpful article from colleagues who are able to articulate this challenge with the nuance required - Reconsidering “inclusive language”. Thank you @drkarleeng.bsky.social @mathisenroger.bsky.social & colleagues www.sciencedirect.com/science/arti...
Karleen Gribble (@drkarleeng.bsky.social) reposted
The Sullivan Review on data collection recommended against "sex assigned at birth" due to inaccuracy. It also had this graph. Females face sex discrimination globally, at the extreme this is fatal. The idea that anyone assigns infants to this fate is extremely offensive www.gov.uk/government/p...
Chris Pook (@drchrispook.bsky.social) reply parent
Isn't your party de facto insolvent thanks to all of the sex discrimination claims against you from former members expelled under your party's McCarthyism?
BioMassSpec (@realbiomassspec.bsky.social) reposted
The metabolic signature of salt intake: a cross-sectional analysis from the SCAPIS-study #NutrMetab #MassSpec nutritionandmetabolism.biomedcentral.com/articles/10....
Chris Pook (@drchrispook.bsky.social) reply parent
There you go again.
Chris Pook (@drchrispook.bsky.social) reply parent
And finally, most damningly, why would anyone listen to evidence-based arguments for sustainability from people who so arrogantly insist, against all reason, that humans can change sex and that transvestites are the most oppressed people in modern society?
Chris Pook (@drchrispook.bsky.social) reply parent
How many court cases for sex discrimination are the green party facing at the moment? They have publicly declared themselves to be functionally insolvent, based on their potential liabilities from these cases. What's Polanski going to do different from the neoMcCarthyism of the previous leadership?
Chris Pook (@drchrispook.bsky.social) reply parent
No.
Chris Pook (@drchrispook.bsky.social) reply parent
No. Genital surgery doesn't change your sex. Sex is binary and in mammals, such as humans, immutable.
Chris Pook (@drchrispook.bsky.social) reply parent
Forgive me if I can't find anything a self-confessed "furry" says to be in the least engaging or interesting.
Chris Pook (@drchrispook.bsky.social) reply parent
Thank you for speaking out, John.
Chris Pook (@drchrispook.bsky.social) reply parent
What is a woman, George?
Chris Pook (@drchrispook.bsky.social) reply parent
Oh, believe me, George I can do much, much better. That was just the lowest of many hanging fruit. Would you like me to explain in detail why Polanski is to green politics what botulism is to a dinner party?
Chris Pook (@drchrispook.bsky.social) reply parent
Thank you for sharing your opinion.
Chris Pook (@drchrispook.bsky.social) reply parent
Except it's true! He is actually on video making this claim! The green party are dead. They're ideologically adrift and, thanks to their penchant for inflicting McCarthyism upon anyone who knows sex matters and is immutable in mammals, such as humans, they're also bankrupt!
Chris Pook (@drchrispook.bsky.social) reply parent
I don't think the green party needs to be led by someone who told women he could increase their breast size using hypnosis. I'm not even joking. Polanski is on video claiming this. Google it.
Chris Pook (@drchrispook.bsky.social) reply parent
The fact that you have focussed on hair splitting instead of defending the appalling lack of evidence to support transing confused children is really rather revealing. I don't think you're here to engage in good faith. Goodbye.
Chris Pook (@drchrispook.bsky.social) reply parent
So, in my tweet I used Cass as the most obvious example of several systematic reviews which have all found the evidence base to support the transing of confused children to be very weak. I don't have to apologise for my lack of specificity.
Chris Pook (@drchrispook.bsky.social) reply parent
I mean, it seems like you're really keen to establish that the Cass Review found the evidence in support of transing confused children to rank third on a scale of three levels, rather than fourth on a scale of four levels. Do you think that's a meaningful distinction, bro?
Chris Pook (@drchrispook.bsky.social) reply parent
What argument do you think I'm making?
Chris Pook (@drchrispook.bsky.social) reply parent
How many of these people got arrested, do you think? Terfisaslur.com
Chris Pook (@drchrispook.bsky.social) reply parent
In your opinion, is it reasonable to expect non-experts to perfectly recall which reviews use which system? I've only ever published one systematic review, and I found it incredibly difficult and at the margins of my comfort zone.
Chris Pook (@drchrispook.bsky.social) reply parent
So, we've established that there are multiple grading systems, of which GRADE is one. And that some of them use numerical scores in combination with categories, such as Ottawa-Newcastle, while some use just categories.
Chris Pook (@drchrispook.bsky.social) reply parent
You haven't answered my question. Do you know what you're talking about so confidently, and rudely, about? And yes, I have read the final report.
Chris Pook (@drchrispook.bsky.social) reply parent
You've yet to come up with a reason why we should treat people as if they can change sex when we know they can't.
Chris Pook (@drchrispook.bsky.social) reply parent
What are the categories used in the Ottawa-Newcastle scheme? What about the MMAT?
Chris Pook (@drchrispook.bsky.social) reply parent
For others reading this, I'll play along with this charade. 1) Kemi Badenoch is talking about gender critical members of government*commissioning* the Cass Review. Not about Dame Professor Cass being "GC" herself. 2) GRADE criteria: en.m.wikipedia.org/wiki/GRADE_a... Screenshot.
Chris Pook (@drchrispook.bsky.social) reply parent
His position is indistinguishable from mysticism.
Chris Pook (@drchrispook.bsky.social) reply parent
No. He doesn't. He argues that snake oil might actually work, if we gave it a chance and ignored the negative results and had faith in the healing power of Lord Transus.
Chris Pook (@drchrispook.bsky.social) reply parent
No. That's just an unsubstantiated smear. And the evidence I am dismiss was *very* low quality. You seem to be unaware that most children with discomfort about their developing bodies grow out of it if allowed to do so unmolested by gender activists.
Chris Pook (@drchrispook.bsky.social) reply parent
Hi George, long time green voter here. A PhD in environmental toxicology, so a huge fan of your environmentalism. A biologist, so a huge fan of rewilding & preservation. Massive fan of renewables & net zero too. But, before I endorse your proposal, I have a question for you: What is a woman?
Brap (@brap.bsky.social) reposted
www.telegraph.co.uk/news/2025/09... Glad to see the PM thinks this is mad too!
Marwoodl ♀️ (@marwoodl.bsky.social) reposted
Comedian Graham Linehan said “I was arrested at an airport like a terrorist, locked in a cell like a criminal, taken to hospital because the stress nearly killed me and banned from speaking online — all because I made jokes that upset some psychotic crossdressers.” 🎁 www.thetimes.com/article/85ef...
Chris Pook (@drchrispook.bsky.social) reply parent
So, let me tell you about these people called detransitioners whose lives were ruined by clinicians pushing irreversible medical interventions on children. Who is Keira Bell? Who is Chloe Cole? Who is Prisha Moseley? Who is Richie Tulip? Who is Sinead Watson? Who is Joseph Pear?
Chris Pook (@drchrispook.bsky.social) reply parent
LOL do you even know who "Natacha Kennedy" is???
Chris Pook (@drchrispook.bsky.social) reply parent
Interestingly there's only six systematic reviews listed on the journal's website. I wonder where the seventh is? web.archive.org/web/20240410...
Chris Pook (@drchrispook.bsky.social) reply parent
Taylor J, Hall R, Langton T, et al. Care pathways of children and adolescents referred to specialist gender services: a systematic review. Archives of Disease in Childhood 2024;109:s57-s64. adc.bmj.com/content/109/...
Chris Pook (@drchrispook.bsky.social) reply parent
Taylor J, Mitchell A, Hall R, et al. Masculinising and feminising hormone interventions for adolescents experiencing gender dysphoria or incongruence: a systematic review. Archives of Disease in Childhood 2024;109:s48-s56. adc.bmj.com/content/109/...
Chris Pook (@drchrispook.bsky.social) reply parent
Taylor J, Mitchell A, Hall R, et al. Interventions to suppress puberty in adolescents experiencing gender dysphoria or incongruence: a systematic review. Archives of Disease in Childhood 2024;109:s33-s47. adc.bmj.com/content/109/...
Chris Pook (@drchrispook.bsky.social) reply parent
Heathcote C, Taylor J, Hall R, et al. Psychosocial support interventions for children and adolescents experiencing gender dysphoria or incongruence: a systematic review. Archives of Disease in Childhood 2024;109:s19-s32. adc.bmj.com/content/109/...
Chris Pook (@drchrispook.bsky.social) reply parent
Hall R, Taylor J, Hewitt CE, et al. Impact of social transition in relation to gender for children and adolescents: a systematic reviewArchives of Disease in Childhood 2024;109:s12-s18. adc.bmj.com/content/109/...
Chris Pook (@drchrispook.bsky.social) reply parent
Taylor et al. (2024). Characteristics of children and adolescents referred to specialist gender services: a systematic review. adc.bmj.com/content/109/...
Chris Pook (@drchrispook.bsky.social) reply parent
And you're still relying on the dishonest framing of the "Cass report" when what Cass actually lead was The Independent Review of Gender Identity Services for Children and Young People. The final report was just a synthesis of seven systemativ reviews. Here's links to them:
Chris Pook (@drchrispook.bsky.social) reply parent
Cass was one of, if not the tope paediatrician in the entire country. She was absolutely world class. The idea that she lacked expertise in evidence-based treatment for mentally ill children is just ridiculous.
Chris Pook (@drchrispook.bsky.social) reply parent
So, I think you're relying on the technicality here that the final report itself wasn't peer reviewed, but was a synthesis of seven systematic reviews which were peer reviewed. I'm happy to acknowledge that, but your use of it as a "gotcha" is really rather dishonest.
Chris Pook (@drchrispook.bsky.social) reply parent
Nice straw man. Things that don't exist don't begin to existence just because you really want them to.
Chris Pook (@drchrispook.bsky.social) reply parent
So, I think you're relying on the technicality here that the final report itself wasn't peer reviewed, but was a synthesis of seven systematic reviews which were peer reviewed. I'm happy to acknowledge that, but your use of it as a "gotcha" is really rather dishonest.
Chris Pook (@drchrispook.bsky.social) reply parent
Gender isn't a pathology, so there's no such thing as "gender medicine".
Chris Pook (@drchrispook.bsky.social) reply parent
I'm afraid you have been misinformed.
Chris Pook (@drchrispook.bsky.social) reply parent
I'm afraid you have been misinformed.
Prof Sam Illingworth (@samillingworth.com) reposted
🥫 Ultra-processed food & mortality A study of 186,000+ UK adults found that certain additives (like flavours, sweeteners, and colouring agents) were linked to higher mortality risk. 🔗 www.thelancet.com/journals/ecl... #SciComm #Nutrition #UPFs 🧪
Chris Pook (@drchrispook.bsky.social) reply parent
One of the useful things about peer review is it means you have to be able to demonstrate to other scientists that your arguments are systematic and address tangible and significant knowledge gaps in the literature. If you can't show that then why would I read your work?
Chris Pook (@drchrispook.bsky.social) reply parent
If your arguments have any merit then I encourage you to submit your work to a journal for peer review. Then I'll read them.
Chris Pook (@drchrispook.bsky.social) reply parent
Just because two thirds of the "medicine" that you refer to isn't evidence-based doesn't make it actual medicine.
Chris Pook (@drchrispook.bsky.social) reply parent
Dame Professor Cass lead the systematic review of the UK's child gender medicine program. Her work is world renowned. You can read it for yourself here. #CassReview webarchive.nationalarchives.gov.uk/ukgwa/202503...
Chris Pook (@drchrispook.bsky.social) reply parent
I'm referring to Baroness Cass. Former president of the Royal College of Paediatrics & Child Health, former chair of the British Academy of Childhood Disability, founder of the Rett Clinic for Children, appointed Officer of the Order of the British Empire for services to child health.
Chris Pook (@drchrispook.bsky.social) reply parent
No. I am dismissing evidence which has been systematically assessed and found to be of very low quality. Who is Dame Professor Hillary Cass?
Chris Pook (@drchrispook.bsky.social) reply parent
Good one. Thank you for sharing.
Chris Pook (@drchrispook.bsky.social) reply parent
You don't seem to understand that there's no such thing as medicine without evidence. If there's no good evidence that an intervention will benefit someone then giving them that intervention regardless isn't medicine. It's ideology. It's FGM. It's trepanning. It's giving anorexics liposuction.
Chris Pook (@drchrispook.bsky.social) reply parent
I just finished Department Q on Netflix. Beautifully shot and acted. Such good entertainment. A bit grisly in places though.
Compound Interest | Chemistry infographics (@compoundchem.com) reposted
As summer fades, dahlias are blooming. This graphic looks at the chemical cause of their colours and why you won't spot a blue one! www.compoundchem.com/2021/09/12/d... #ChemSky 🧪
Chris Pook (@drchrispook.bsky.social) reply parent
Sex is absolutely binary and in mammals, such as humans, immutable. Gender nonconformity is perfectly natural and shouldn't be reified or pathologised. Lying to children that they can change sex, or that sex is anything other than binary and immutable, is abuse.
Chris Pook (@drchrispook.bsky.social) reply parent
Several national reviews of the use of puberty blockers by actual scientists have shown no good evidence to support their use & no evidence to show they're reversible. Which is obvious to a biologist, given that puberty is a temporary stage in development. www.health.govt.nz/system/files...
Chris Pook (@drchrispook.bsky.social) reply parent
209 adolescent (12-17yo) girls underwent elective mastectomy as part of "gender affirming care" in the US between 2012 & 2020. pubmed.ncbi.nlm.nih.gov/36248210/
Chris Pook (@drchrispook.bsky.social) reply parent
No. Children are not "independent people". Children need firm boundaries and constant support. The state only intervenes in the most desperate of cases as a last resort. That is because the state is a terrible substitute for parenting.
Chris Pook (@drchrispook.bsky.social) reply parent
Lies. Absurdly transparent lies.
Chris Pook (@drchrispook.bsky.social) reply parent
Yes, it is. But not for the reasons that you think.
Chris Pook (@drchrispook.bsky.social) reply parent
You'll be busy on this platform then. 🙄
Chris Pook (@drchrispook.bsky.social) reply parent
Children are children. They're not mature, independent people. The reason parents have agency over children's lives is to safeguard them from people who wish to exploit their innocence and naivety with malicious intent.
Chris Pook (@drchrispook.bsky.social) reply parent
Hang on a sec. "Teenagers" covers ages 13 to 19. The lower age is not the same as the upper. Are you suggesting that 13 yr olds can consent to irreversible medical treatment? If they can consent to that aren't you the one here making inappropriate arguments about ages of consent?
Chris Pook (@drchrispook.bsky.social) reply parent
Their reasons are entirely coherent. Like much of their policy platform, it's reactionary conservatism: "The woke majority are against it, so we're for it."
Chris Pook (@drchrispook.bsky.social) reply parent
I'm sorry about your plumbing. That's a pretty shitty deal.
Chris Pook (@drchrispook.bsky.social) reply parent
You can't because one doesn't exist. Sex is absolutely binary. It is not a spectrum. There is no such thing as a "sperg" or a "spegg".
Chris Pook (@drchrispook.bsky.social) reply parent
I could respond with "my three biology degrees and a career in biochemistry research", but that would be a type of logical fallacy called an argument from authority. Instead I'll just invite you to name the third gamete.
Chris Pook (@drchrispook.bsky.social) reply parent
That article has been comprehensively debunked several times over the years. It is disinformation. Jerry Coyne's probably done the most complete deconstruction of it. whyevolutionistrue.com/2022/08/29/o...
Chris Pook (@drchrispook.bsky.social) reply parent
But you are male or female. Regardless of how many surgeries or drugs you take. And that's okay. Why would it not be? We're all human. Pretending you're something you're not is for children and the mentally unwell.
Chris Pook (@drchrispook.bsky.social) reply parent
No, I'm not a state representative. You still can't change sex.
Chris Pook (@drchrispook.bsky.social) reply parent
Intersex is an obsolete misnomer. I think you mean a disorder of sexual development. Sex is binary and in mammals, such as humans, immutable. Most people with DSDs remain unequivocally male or female. It is unethical to perform unnecessary surgery on infants born with DSDs.
Oded Rechavi (@odedrechavi.bsky.social) reposted
Scientists develop a novel method sensitive enough to detect the contribution of serving on committees to your chances of getting promoted
Chris Pook (@drchrispook.bsky.social) reply parent
I think we're all on the same side of this issue and I think you've both made excellent points. Thank you.
Chris Pook (@drchrispook.bsky.social) reply parent
Ok, I'm not going to detect chlorpyrifos in untargeted lipidomics data as the concentrations measured are in the parts-per-trillion range. Here's the method paper for the data in JAMA. They extracted 4g of plasma or serum to reach that sensitivity. www.sciencedirect.com/science/arti...
Chris Pook (@drchrispook.bsky.social) reply parent
That paper used GC-MS so I looked up an LC-MS method paper. I wanted to know if I could see it in any of my data. Can someone explain how these guys are detecting it at m/z 352 when the MIM is 349? pmc.ncbi.nlm.nih.gov/articles/PMC... Does it gain a saturation?
Chris Pook (@drchrispook.bsky.social)
Interesting paper on chlorpyrifos and infant neurodevelopment. jamanetwork.com/journals/jam...
Chris Pook (@drchrispook.bsky.social)
One of the more annoying things about living on Aotearoa New Zealand is the time zone difference for webinars scheduled on European or American time. This one looks fascinating , but it's at 3am. #metabolomics us06web.zoom.us/webinar/regi...